The Skin Biotic

Name: The Skin Biotic
Brand: AWvi
SKU: S/101A
Price: 64.0 EUR
Availability: InStock

S/101A

The Skin Biotic is a next-generation nutraceutical developed to modulate the gut microbiome to support actively skin health from within. Acting along the gut–skin axis, it addresses upstream physiological mechanisms that drive inflammation, immune dysregulation and cutaneous imbalance. Its formulation combines a meticulously dosed prebiotic, three proprietary probiotic strains and highly bioavailable forms of retinol and D-biotin, selected for their ability to influence microbial activity, epithelial integrity and systemic inflammatory signalling.

Through targeted microbial reprogramming, it contributes to systemic and dermatological homeostasis across all skin types and inflammatory-prone profiles, including acne, rosacea, atopic tendencies and sensitivity-related flare-ups. It also plays a key role in maintaining skin longevity by supporting resilience against intrinsic and extrinsic ageing processes.

This solution forms the core of AWvi’s physiology-based approach, where skin regeneration and age-related preservation begin with internal regulation. It can be used as a stand-alone strategy or in synergy with AWvi’s cosmeceutical formulations.

ALL SKIN TYPES ∙ ALL GENDERS

€64,00

How to use

Take 1 sachet a day, preferably in the morning, 30 minutes before breakfast, dissolved directly in the mouth or in a small amount of water.

How it works

The Skin Biotic represents a groundbreaking nutraceutical innovation that capitalizes on the intricate interplay between the gut and the skin. This symbiotic relationship, often referred to as the 'gut-skin axis,' allows us to tap into the unique benefits of specific probiotic strains, thereby fostering comprehensive skin health, overall well-being, and an improved appearance, not confined to the face but extending to the entirety of the body.

Within our probiotic complex, which comprises three PROPRIETARY strains, lies the essence of our holistic approach. These strains have been carefully curated and fine-tuned to work in concert, culminating in a synergistic effect that maximizes skin-related advantages. By nurturing a harmonious microbiome balance, we bolster the skin's natural defense mechanisms while supercharging its regenerative prowess.

Furthermore, The Skin Biotic incorporates indispensable vitamins, notably Retinol and D-Biotin, strategically selected due to their pivotal roles in supporting skin cellular metabolism.

Our quest for excellence extends to the selection of probiotic strains, where we delve into the intricacies of DNA analysis. In our journey to uncover the most suitable strains, we have come to appreciate the vast diversity within the Lactobacillus genus. It is crucial to recognize that each strain within this extensive family possesses distinct characteristics and capabilities.

Our commitment to precision is exemplified by our approach, built upon two pillars: Integration and Correct Dosage.

We introduce ingredients that seamlessly integrate with the body's natural chemistry and biology. This ensures that our supplement becomes an integral part of your daily well-being, working in harmony with your system.

The emphasis on precise dosing is paramount.

Achieve the optimal balance of ingredients, rather than relying on quantity, is the key to unlocking the full potential of our product. The probiotics must not only be alive but also present in the correct quantity when administered.

The quantity of living organisms in a probiotic dose is indicated on the label and is typically measured in CFU (colony forming units). This quantity should align with the dosage used in the related clinical trial that proved the efficacy of the specific bacterial strain. Unlike some products that tout high CFU (colony-forming units) counts, we prioritize efficacy, understanding that excess can often lead to undesirable reactions.

Our unwavering commitment to quality extends to all AWvi products. We adhere to pharmaceutical-grade R&D and manufacturing practices (our internal nutraceutical production line being located within a GMP—Good Manufacturing Practice—pharmaceutical facility that is certified by the Italian Medicines Agency), ensuring the safety and longevity of our supplement, right up to their expiration date.

In essence, The Skin Biotic transcends the conventional supplement paradigm.

Ingredients

Ingredients:

FRUCTO-OLIGOSACCHARIDES, SWEETENER: MANNITOL, LIMOSILACTOBACILLUS REUTERI, LACTICASEIBACILLUS RHAMNOSUS, LACTIPLANTIBACILLUS PLANTARUM, VITAMIN A (RETINYL ACETATE), BIOTIN (D-BIOTIN).

Focus on supplement hero ingredients:

L. Plantarum AW001

It improves skin hydration by increasing natural hyaluronic acid production.

It aids in producing essential lipids and proteins that strengthen the skin's protective layer, reducing susceptibility to environmental stressors and irritants.

It can modulate the skin's immune response, potentially reducing allergic reactions and other immune-related conditions.

It helps soothe skin inflammation and is beneficial in managing atopic dermatitis and sensitive skin.

This strain exhibits antimicrobial activity against harmful skin bacteria, essential in managing acne and bacterial skin infections, contributing to a healthier skin microbiome.

It also exhibits antioxidant properties, protecting skin cells from free radical damage. This protection helps reduce the signs of aging and environmental skin damage.

L. Reuteri AW002

It plays a crucial role in mitigating oxidative stress in skin cells, which is a significant factor in the aging process. This action helps in reducing the appearance of wrinkles and other signs of aging.

It is also known for its potential to promote tissue regeneration, aiding in the skin's natural healing process and improving recovery from skin damage.

This strain is particularly effective in reducing skin inflammation, making it beneficial for conditions like acne, eczema, and psoriasis. Its production of substances like reuterin and histamine helps modulate immune responses, which is key in managing these inflammatory skin conditions.

Lactobacillus reuteri enhances the skin's barrier function by increasing ceramide production. Ceramides are essential lipids that help the skin retain moisture and protect against external irritants and pathogens, contributing to overall skin health and resilience.

L. Rhamnosus AW003

It enhances the skin's barrier function by improving tight junction protein production, crucial for protecting against pollutants and allergens.

It modulates immune responses, reducing allergic reactions and inflammation, beneficial for conditions like eczema and atopic dermatitis.

This probiotic balances the skin microbiome, inhibiting harmful bacteria, thereby improving skin health and resilience.

Its anti-inflammatory properties soothe inflamed skin, helping in conditions like acne and rosacea.

Additionally, Lactobacillus rhamnosus aids in skin hydration, enhancing natural moisture retention and reducing dryness.

Its antioxidant properties protect against oxidative stress and free radical damage, slowing the aging process and mitigating environmental skin damage.

Retinol and D-Biotin

Retinol (Vitamin A) enhances skin cell turnover, leading to improved texture and tone.
It accelerates the shedding of dead skin cells and the generation of new ones, influencing gene expression related to skin health.

Aiding in collagen production, it's crucial for reducing wrinkles and enhancing firmness.

It also offers protection against environmental stressors like UV radiation and pollution, thanks to its antioxidant capabilities, and reduces hyperpigmentation and age spots, contributing to an even skin tone.

D-biotin (Vitamin B8) is critical for the production of fatty acids, forming the foundation of cell membranes and contributing to a healthy skin barrier and hydration.

It plays a role in fat metabolism and cell growth, essential for the overall health and appearance of the skin.

It may help in reducing skin inflammation and redness, beneficial for conditions like rosacea and eczema.

Clinically

proven

Lactose

free

Gluten

free

Renewable

sources

Local

sources

Vegan

friendly

Evidence-backed outcomes

Transformative results in 8 weeks

Clinical Results
Wrinkles
Radiance
Smoothness
Skin barrier
Impurities

88%

reduction in wrinkles and fine lines

100%

increase in skin radiance

96%

increase in skin moisturisation

79%

increase in skin smoothness

71%

improvement in skin barrier function

88%

decrease in skin impurities

Percentage of subjects showing a significant improvement after 8 weeks (clinically measured parameters). Endpoints are measured using techniques currently accepted in the cosmetic field while biases are minimized by procedure(s) standardization according to ISO 9001 QMS.

IN
OUT
IN & OUT

The Skin Biotic only

A systemic inside-out approach that modulates skin physiology via the gut–skin axis, integrating microbial signalling, immune regulation, and metabolic pathways.

Topical solutions only

A targeted outside-in intervention reinforcing epidermal integrity, barrier function, and tissue renewal processes.

Combined approach

An integrated In & Out strategy activating concurrent systemic and dermal mechanisms, with clinically measured efficacy amplified by 2.1×

8-week clinical efficacy study performed according to 4 distinct protocols:

1. PLACEBO: Placebo supplement + Placebo topical solutions

2. IN: The Skin Biotic + Placebo topical solutions

3. OUT: Placebo supplement + AWvi topical solutions

4. IN + OUT: The Skin Biotic + AWvi topical solutions

BEFORE

AFTER

Clinically proven results

Wrinkles and fine lines reduction

Up to 34% wrinkles and fine lines reduction 1

Over x4.2 improvement after 8 weeks using The Skin Biotic 2

Target: 58 years old subject
Protocol: use of The Skin Biotic combine with 3 placebo topicals for 8 weeks

Pictures in T0 (clinical study start) and T8 (after 8 weeks)

1. Results from the reference group using The Skin Biotic with three placebo topicals.
2. Comprehensive improvement provided by 'The Skin Biotic' active supplement, compared to a combination of placebo solutions composed of one supplement and three topical products.