The Active Cream

S/101D

The Active Cream is a biomimetic cosmeceutical formulation developed to provide round-the-clock reinforcement of skin barrier function, restore hydration and support epidermal repair. Acting at the interface of surface protection and structural renewal, it provides lipid replenishment, moisture retention and defence against both environmental and endogenous stressors.

Formulated for daily use, it is particularly suited to dry skin, combination skin, sensitive skin, ageing skin, dehydrated skin and redness-prone profiles. It is also appropriate for inflammatory skin conditions such as acne, rosacea, dermatitis, psoriasis and eczema, where barrier dysfunction and immune imbalance are commonly involved.

The Active Cream combines medium to high molecular weight sodium hyaluronate, biotech-derived ectoin and bioidentical lipids to support epidermal integrity and promote cutaneous homeostasis. It may be used as a stand-alone moisturising treatment or as the final step in a multi-layered skin protocol, including systemic interventions such as The Skin Biotic.

ALL SKIN TYPES  ∙  ALL GENDERS

€128,00

How to use

In the morning and evening, apply on dry, cleansed skin to face and neck, as well as the delicate eye area.

How it works

The Active Cream is an example of innovative formulation, deeply rooted in cutting-edge biotechnological research.

 

Designed for rapid absorption and extended action throughout the day and night, our cream represents the epitome of synergistic science. Each ingredient, unique in its own right, collaboratively enhances the function of the others.

 

We begin with Ectoin, a revolutionary post-biotic molecule obtained through advanced biofermentation techniques involving a non-GMO bacterial strain. Originating from the extreme saline conditions of the desert, Ectoin acts as a cellular shield and metabolic booster. It significantly elevates the anti-aging attributes of the formula, enhancing skin structure, reducing wrinkles, and strengthening elasticity and smoothness.

 

Next, we have a highly specialized form of olive oil triglycerides, manipulated through modern chemical methodologies like purification, extraction, and isolation to achieve unparalleled potency. Since triglycerides naturally occur in our physiological systems, this harmonizes perfectly with the skin's native chemistry.

 

The hyaluronic acid incorporated into this formula ranges from medium to high molecular weights, ensuring comprehensive skin benefits across diverse skin needs.

 

The end result is a scientifically validated formula, rapid-absorbing and long-lasting, offering unmatched hydration, rejuvenation, and balance to the skin's ecosystem, bolstering its natural defenses, ensuring robust protection against external aggressors. 

 

The cream's rapid absorption quality also allows for subsequent makeup application. This cream provides a holistic care regimen, effective from morning to night.

 

The formula has been meticulously developed to meet the needs of individuals of any age, gender, and skin complexion.

Ingredients

CITRUS SINENSIS (ORANGE) FRUIT EXTRACT, TRIOLEIN, BUTYLENE GLYCOL, C10-18 TRIGLYCERIDES, GLYCERYL DIOLEATE, POLYGLYCERYL-3 STEARATE, ECTOIN, GLYCERIN, SODIUM HYALURONATE, SUNFLOWER SEED OIL GLYCERIDES, C15-19 ALKANE, XANTHAN GUM, POLYGLYCERYL-6 LAURATE, POLYGLYCERIN-6, CETEARYL ALCOHOL, CAPRYLYL GLYCOL, SORBITAN OLEATE, SORBITAN ISOSTEARATE, ETHYLHEXYLGLYCERIN, O-CYMEN-5-OL, POTASSIUM SORBATE, PARFUM (FRAGRANCE).

Focus on topical hero ingredients:

Active Water

Most skincare products are composed largely of water (up to 85%, by volume), which serves primarily as a base. We have made this essential component an active ingredient.

 

Our active water is upcycled, extracted from the non-edible portions of organic Mediterranean green mandarins (The Power Serum) and red oranges (The Gentle Cleanser and The Active Cream).

 

Compared to demineralised or distilled water, our microbiologically pure water offers a protective effect against oxidation, UV rays, and pollution.

 

Our active water also has anti-inflammatory properties and forms a protective film that strengthens the skin barrier. Moreover, it contains a type of salt that is recognised by the body and assists in the absorption of other ingredients.

Biomimetic Hyaluronic Acid

Hyaluronic acid (HA) is a key molecule involved in skin moisture, with the ability to hold up to 1,000 times its weight in water.

 

Ours comes in a full spectrum of molecular sizes, mimicking the HA produced by the human body and better able to counteract its gradual, age-related decline.

 

Molecules of varying sizes penetrate the skin at different depths, with larger molecules working on the surface and smaller ones reaching deeper layers.

 

Our topical formulas contain HA molecules of one or more sizes, selected according to each product specific function.

 

Our HA works to enhance skin moisturisation and reinforce the skin barrier, contributing to an overall improvement in skin health. It also offers a direct lifting effect, stimulates collagen production, and induces synthesis of elastin in fibroblasts.

 

These actions increase skin elasticity and smoothness and decrease the depth of fine lines and wrinkles.

Ectoin

Ectoin is an amino acid derivative discovered in the desert, where it was found to protect microorganisms against extreme conditions.

 

Our purified ectoin is a biotech product, precisely characterised from a chemical and biological perspective. It is made by bio-fermenting a non-GMO bacterial strain selected for its ability to enhance skin health.

 

Our ectoin actively supports the restoration of skin homeostasis, fortifying skin’s microbiotic defences against environmental stressors and promoting the synthesis of skin-strengthening peptides.

 

It also promotes cell viability and enhances cell metabolism while improving skin texture and elasticity and reducing the appearance of fine lines and wrinkles.

Biomimetic Triglycerides

Triglycerides are naturally occurring compounds that help to maintain healthy skin by providing a source of energy for skin cells, preserving the skin’s protective barrier, and reducing skin irritation and redness with their anti-inflammatory properties. 

 

They also contribute to the formation of lipids that keep skin hydrated, preventing water loss and helping to maintain its structure and function.

 

Our triglycerides have similar properties to those that occur naturally within the body. Their biocompatibility ensures high penetration of both active and functional ingredients while making our formulas easier to apply and more comfortable on the skin.

 

Our triglycerides are derived exclusively from locally sourced Italian, non-GMO olives using purification, extraction, and isolation processes that reduce our carbon footprint.

Clinically

proven

Derm
tested

Sensitive
skin

Renewable

sources

Local 

sources

Vegan 

friendly

Evidence-backed outcomes

Transformative results in 8 weeks

  • Clinical Results

  • Radiance

  • Wrinkles

  • Smoothness

  • Skin barrier

  • Matt complexion

92%

increase in skin radiance

75%

reduction in wrinkles and fine lines

100%

increase in skin hydration and moisturisation

83%

increase in skin smoothness

92%

improvement in skin barrier function

71%

increase in matt complexion

Percentage of subjects showing a significant improvement after 8 weeks (clinically measured parameters). Endpoints are measured using techniques currently accepted in the cosmetic field while biases are minimized by procedure(s) standardization according to ISO 9001 QMS.

  • IN

  • OUT

  • IN & OUT

The Skin Biotic only

A systemic inside-out approach that modulates skin physiology via the gut–skin axis, integrating microbial signalling, immune regulation, and metabolic pathways.

Topical solutions only

A targeted outside-in intervention reinforcing epidermal integrity, barrier function, and tissue renewal processes.

Combined approach

An integrated In & Out strategy activating concurrent systemic and dermal mechanisms, with clinically measured efficacy amplified by 2.1×

8-week clinical efficacy study performed according to 4 distinct protocols:

1. PLACEBO: Placebo supplement + Placebo topical solutions

2. IN: The Skin Biotic + Placebo topical solutions

3. OUT: Placebo supplement + AWvi topical solutions

4. IN + OUT: The Skin Biotic + AWvi topical solutions

BEFORE
AFTER

Clinically proven results

Radiance improvement

Up to 65% radiance improvement 1

Over x3.6 improvement after 8 weeks using the AWvi topical solutions 2

Target: 63 years old subject 
Protocol: use of The Skin Biotic combine with 3 placebo topicals for 8 weeks

Pictures in T0 (clinical study start) and T8 (after 8 weeks)

1. Results from the reference group using three AWvi active topicals with one placebo supplement.
2. Comprehensive improvement provided by the three AWvi active topical products, compared to a combination of placebo solutions composed of one supplement and three topical products.

BEFORE
AFTER

Clinically proven results

Wrinkles and fine lines reduction

Up to 35% wrinkles and fine lines reduction 1

Up to 34% reduction after 1 hour 1

Over x3 improvement after 8 weeks using the AWvi topical solutions 2

Target: 48 years old subject 
Protocol: use of The Skin Biotic combine with 3 placebo topicals for 8 weeks

Pictures in T0 (clinical study start) and T8 (after 8 weeks)

1. Results from the reference group using three AWvi active topicals with one placebo supplement.
2. Comprehensive improvement provided by the three AWvi active topical products, compared to a combination of placebo solutions composed of one supplement and three topical products.

BEFORE
AFTER

Clinically proven results

Smoothness improvement

Up to 20% smoothness increase 1

Over x4.9 improvement after 8 weeks using the AWvi topical solutions 2

Target: 61 years old subject 
Protocol: use of The Skin Biotic combine with 3 placebo topicals for 8 weeks

Pictures in T0 (clinical study start) and T8 (after 8 weeks)

1. Results from the reference group using three AWvi active topicals with one placebo supplement.
2. Comprehensive improvement provided by the three AWvi active topical products, compared to a combination of placebo solutions composed of one supplement and three topical products.

BEFORE
AFTER

Clinically proven results

Skin barrier function improvement

Up to 27% skin barrier function improvement 1

Over x3.7 improvement after 8 weeks using the AWvi topical solutions 2

Target: 62 years old subject 
Protocol: use of The Skin Biotic combine with 3 placebo topicals for 8 weeks

Pictures in T0 (clinical study start) and T8 (after 8 weeks)

1. Results from the reference group using three AWvi active topicals with one placebo supplement.
2. Comprehensive improvement provided by the three AWvi active topical products, compared to a combination of placebo solutions composed of one supplement and three topical products.

BEFORE
AFTER

Clinically proven results

Matt complexion improvement

Up to 44% matt complexion improvement 1

Target: 48 years old subject 
Protocol: use of The Skin Biotic combine with 3 placebo topicals for 8 weeks

Pictures in T0 (clinical study start) and T8 (after 8 weeks)

1. Results from the reference group using three AWvi active topicals with one placebo supplement.
2. Comprehensive improvement provided by the three AWvi active topical products, compared to a combination of placebo solutions composed of one supplement and three topical products.

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The Active Cream

€128,00