Rosacea is often reduced to visible redness, but it is more complex than that. It is a long-term skin condition that can involve flushing, persistent redness, visible vessels, burning, stinging, dryness and inflammatory bumps. Symptoms can vary from person to person, and common triggers may include sunlight, heat, cold weather, stress, alcohol, spicy foods and certain skincare products.
This is why rosacea-prone skin requires more than a purely cosmetic response. Visible redness is only one part of the picture. For many people, the challenge also involves barrier fragility, vascular reactivity, inflammation, sensitivity and the way the skin responds to daily internal and external stressors.
At AWvi, we believe long-term skin health depends on understanding these deeper mechanisms. The aim is not only to calm a flare when it appears, but to support the biological conditions that help skin become more resilient over time.
A case study supervised by Dr Rachna Murthy

In this AWvi case study, a subject with rosacea-prone skin followed a four-week protocol under the supervision of Dr Rachna Murthy, FRCOphth, Consultant Ophthalmologist, Oculoplastic, Aesthetic and Reconstructive Surgeon. The protocol was assessed using VISIA Skin Analysis, with scans performed at T0, the baseline, and T4, week four.
The protocol combined daily oral intake of The Skin Biotic with twice-daily application of The Gentle Cleanser and The Active Cream. The objective was to support the skin from the inside out and the outside in, by addressing the gut-skin axis, the skin barrier, microbial balance and visible signs of inflammation.
Dr Murthy’s clinical background makes her perspective particularly relevant. She is listed by FaceRestoration as a London and Cambridge-based Consultant Ophthalmologist, Oculoplastic and Reconstructive Surgeon, and her work sits at the intersection of facial aesthetics, periocular health and regenerative approaches to skin and tissue.
Expert insight
“Rosacea is a complex condition that needs careful diagnosis and a tailored approach, as it can mimic other skin concerns and often involves deeper health factors.
This kind of personalised care is also important when you consider the emotional impact rosacea can have on confidence and daily life.
Tools like VISIA skin analysis help assess the level of inflammation and guide the development of thoughtful, individualised treatment plans.
While aesthetic treatments can ease visible redness and calm inflammation, they mainly address what’s happening on the surface.
To support more lasting results, a longer-term home plan is required, one that helps strengthen the skin barrier, regulate immune responses and restore microbiome balance.”
Dr Rachna Murthy, FRCOphth
Oculoplastic, Aesthetic and Reconstructive Surgeon
Why a biology-led protocol matters
Rosacea management is increasingly understood as requiring a personalised approach. A 2024 clinical review describes rosacea as a chronic dermatosis that may present with flushing, erythema, papules, pustules, visible vessels, burning and stinging, and identifies multimodal approaches as part of clinical management.
This does not mean every person with rosacea-prone skin needs the same protocol. It means that support should be adapted to the visible signs, the level of sensitivity, the skin barrier condition and the triggers that are specific to each individual.
In practical terms, rosacea-prone skin often needs three things at home:
First, it needs gentle daily cleansing that removes irritants without stripping the skin. NHS Inform recommends gentle skincare products for sensitive skin, while the American Academy of Dermatology advises people with rosacea to carefully select skincare products because irritating products can trigger burning, stinging, dryness and flare-ups.
Second, it needs barrier support. A disrupted barrier can make skin more reactive to external stressors, including heat, cold, pollutants and unsuitable products.
Third, it needs internal support, because visible skin reactivity can be influenced by immune balance, lifestyle, stress and the broader relationship between the gut, the microbiome and the skin.
The AWvi protocol used in this case study
Step 1: The Skin Biotic
The protocol began with The Skin Biotic, AWvi’s nutraceutical designed to support the gut-skin axis from within.
In the case study post, The Skin Biotic is positioned as supporting rosacea-prone skin by helping address microbiome modulation, immune regulation and skin barrier recovery from the inside out.
For rosacea-prone skin, this inside-out layer matters because skin reactivity is not only a surface event. The way the body regulates inflammation, oxidative stress and microbial balance can influence how skin responds to triggers.
Step 2: The Gentle Cleanser
The second step was The Gentle Cleanser, applied twice daily.
For rosacea-prone skin, cleansing is not a neutral gesture. If the cleanser is too aggressive, it can increase dryness, discomfort and reactivity. In this protocol, The Gentle Cleanser was used to help preserve the integrity of the skin barrier while removing external irritants gently.
The aim is to cleanse without disrupting the skin’s natural defences, supporting a more stable surface environment for sensitive and reactive skin.
Step 3: The Active Cream
The third step was The Active Cream, also applied twice daily.
In the case study, The Active Cream is presented as supporting rosacea-prone skin by replenishing barrier lipids, calming visible discomfort and reinforcing long-term resilience through biomimetic repair.
For skin that is prone to redness, dryness or burning sensations, this kind of barrier-centred support is essential. The objective is not simply to cover visible redness, but to help the skin recover a stronger, more stable baseline.
Inside out and outside in
This case study reflects AWvi’s central philosophy: skin health is shaped by both internal and external factors.
From the inside, nutrition, the microbiome, immune balance, oxidative stress and recovery capacity all contribute to the way skin behaves. From the outside, daily cleansing, environmental exposure, barrier support and product tolerance influence whether skin remains calm or becomes reactive.
For rosacea-prone skin, these two dimensions cannot be separated. A cleanser may help reduce external irritation, but the skin also needs internal support. A nutraceutical may support microbial and immune balance, but the skin still needs gentle topical care. A cream may help reinforce the barrier, but daily triggers still need to be identified and managed.
This is the role of a structured home protocol: to create continuity between professional assessment and daily care.
What the VISIA case study shows
The VISIA images in this case study show the subject at baseline and after four weeks of the AWvi protocol. In this individual case, the follow-up image suggests a visible improvement in the distribution and intensity of redness after the combined use of The Skin Biotic, The Gentle Cleanser and The Active Cream.
This should not be read as a guaranteed result for every person with rosacea-prone skin. Rosacea is highly individual, and diagnosis and treatment should always be guided by a qualified healthcare professional.
However, the case study illustrates an important principle: when rosacea-prone skin is approached through barrier care, microbiome support and internal regulation, the objective moves beyond the flare. It becomes a question of helping the skin return to better balance.
A longer-term view of rosacea-prone skin
Rosacea-prone skin often requires patience. Triggers need to be identified. The barrier needs time to recover. The skin’s tolerance has to be rebuilt gradually.
For AWvi, the goal is to support this process through a biology-led method that respects the skin’s physiology. This means avoiding aggressive disruption, reinforcing the barrier, supporting the microbiome and working with the body’s natural mechanisms for defence and repair.
Targeting the flare may calm the moment. Targeting the trigger helps support the conditions for longer-term resilience.
Sources:
Dr Rachna Murthy’s FaceRestoration profile
Dr Rachna Murthy’s Maison Restorative profile
Maison Restorative’s article on gut health and skin quality
Dr Rachna Murthy’s PHIN profile
Dr Rachna Murthy’s PubMed-indexed research on thyroid eye disease
Future of Skin Health article: “AWvi: The Future of Skin Health, Bridging Science and Biology”
Dr Rachna Murthy: “How You Can Fortify Your Microbial Mantle™?”
TFOS Ambassador profile: “Rachna Murthy”
The Beauty Triangle event: “Skin and Soul: How to Balance Complexion, Gut and Mind”
The Beauty Triangle Podcast: “Deep Clean: Simple Steps to Detoxification, Inside and Out”