Blemish-prone skin is rarely only a surface concern. When blemishes, comedonal congestion and recurrent inflammation persist, they often reflect a broader pattern of biological imbalance involving microbial disruption, altered barrier function and dysregulated internal signalling.
In this case supervised by Rita Baiguera, Director of SKINdiciotto, the patient presented with marked inflammation, multiple blemishes and comedonal congestion. The objective was not to suppress visible lesions alone, but to understand the conditions allowing the pattern to persist and support the skin towards greater stability over time.
Clinical focus
At baseline, the skin showed visible inflammatory activity, multiple blemishes and congestion. The clinical focus was on gut-related influences, microbiome disruption, barrier dysfunction and glycaemic balance adapted to the patient’s vegan profile.
The protocol was conducted over eight weeks, with photographs taken at T0 baseline and T8, week 8. It combined daily oral intake of The Skin Biotic, twice-daily application of The Gentle Cleanser and twice-daily application of The Active Cream, alongside glycaemic measures adapted to the patient’s vegan profile.
The clinical priorities were:
→ Investigate biological drivers contributing to skin instability
→ Support regulation across the gut-skin axis
→ Improve microbial balance at the skin interface
→ Strengthen barrier function while easing cutaneous inflammation
→ Soothe inflammation and support immune homeostasis
How AWvi supported the skin
The Skin Biotic supported blemish-prone skin from within by helping regulate microbial balance, inflammatory activity and barrier function at a systemic level. The objective was to contribute to a more stable cutaneous environment, with less recurrent congestion and inflammatory expression.
The Gentle Cleanser supported the topical phase by helping reduce surface congestion, excess sebum and pore-clogging impurities while preserving barrier integrity. For blemish-prone skin, cleansing must avoid stripping or disrupting the microbiome, as over-aggressive cleansing can increase reactivity and compromise recovery.
The Active Cream reinforced the external support by helping restore barrier integrity, regulate lipid balance and ease inflammatory stress. Its role was to support skin resilience while maintaining comfort and physiological coherence.
Together, the protocol reflected AWvi’s inside-out and outside-in approach: acting on systemic influences while preserving and strengthening the skin’s external defence systems.
Expert insight
'Blemish-prone skin rarely develops in a vacuum.
What presents clinically as congestion, inflammation and comedonal activity often points to a wider disturbance involving microbial imbalance, altered barrier function and dysregulated internal signalling.
My work begins by understanding the biological conditions that allow this pattern to persist, both systemically and within the skin itself.
From there, the aim is to build a protocol that helps re-establish order across these interconnected functions, so that the skin can regain stability, tolerance and a more regulated inflammatory profile.
When this happens, the change is not only visible. The skin begins to behave differently.'
Rita Baiguera
Director of SKINdiciotto
Visible evolution
After eight weeks, the skin appeared calmer, less inflamed and more regulated. The visible reduction in blemishes and congestion was consistent with improved cutaneous stability and reduced reactivity over time.
The change was not only a matter of surface clarity. It suggested a shift in how the skin was responding: less persistent inflammatory activity, improved tolerance and a more balanced recovery pattern.
This case illustrates a key principle of AWvi’s approach: blemish-prone skin should not be addressed only through external correction. When congestion and inflammation recur, the skin requires support across the systems that influence microbial balance, barrier strength, immune signalling and daily resilience.
Sources:
SKINdiciotto: lo spazio per la “calma della pelle” a Brescia, L’AltraItalia.
Gut-Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions, PubMed.
Acne, Microbiome, and Probiotics: The Gut-Skin Axis, PubMed.
The Skin Microbiome: A New Actor in Inflammatory Acne, PubMed.
Acne and the Cutaneous Microbiome: A Systematic Review of Mechanisms and Implications for Treatments, PubMed.
The Updates and Implications of Cutaneous Microbiota in Acne, PMC.
A Low-Glycemic-Load Diet Improves Symptoms in Acne Vulgaris Patients: A Randomized Controlled Trial, PubMed.
